A proposed method, using a modified form of somatic cell nuclear transfer (SCNT), of producing a biological artifact from which human pluripotent stem cells could be derived.

theroretical procedure where the nucleus from an egg is removed and an altered genome is inserted so that, in theory, a human clone is not created and human pluripotent stem cells can still be harvested; an proposed alternative to somatic cell nuclear transfer (SCNT) or cloning.

Altered Nuclear Transfer would be similar to SCNT; the key difference being that the resulting cells should carry a mutation that causes cell death at the blastocyst stage, thereby never having the potential to develop into a full embryo and thus avoiding the ethical issues with use of embryos.