Definitions for "Aminopterin"
An anticancer drug that belongs to the family of drugs called antimetabolites.
Aminopterin (4-aminopteroic acid), a 4-amino analog of folic acid, is an antimetabolite drug used in chemotherapy. Its antifolate activity was first used by Sidney Farber in 1947 to induce remissions among children with leukemia. Although more potent than methotrexate, it was replaced by methotrexate in the 1950s, due to unpredictable toxicity.
Keywords:  hepatotoxic, phosphorous
Hepatotoxic Phosphorous