Osteodystrophy is a combination of bone disorders that is usually caused by chronic kidney failure (renal disease). The bone disorders affecting patients with osteodystrophy include varying combinations and degrees of osteoporosis, osteomalacia, osteitis fibrosa, and osteosclerosis. [See: Fluoride & Renal Osteodystrophy | Fluoridation, Dialysis, & Osteomalacia