The physiological barrier that separates blood from brain parenchyma. It consists of endothelial cells with tight junctions that are surrounded by a continuous basement membrane and astroglial end-feet. The blood brain barrier is the central modulator of neuroimmune function in the CNS (6).
A highly selective barrier formed by blood vessels and a type of brain cell, astrocytes, that allows only appropriate molecules to cross from blood to brain. eg oxygen, sucrose and it aimed at keeping harmful molecules out of the brain.
is the barrier that is designed to protect the brain from harmful, unnatural chemicals circulating in the blood. There are precise sites in the BBB which are specifically designed to recognize amino acids like tryptophan so that they can be transported to the brain where they are needed.
A protective barrier that allows only certain substances to enter the brain from blood vessels
A system of astrocytes and capillaries in the brain that prevents the passage of specific substances.
a collection of endothelial cells that press together to block substances (including folic acid) from entering the brain while letting others (such as l-methylfolate) pass through
Black's medical dictionary, G Macpherson ed; 38th ed A functional semi-permeable membrane separating the brain and cerebrospinal fluid from the blood. It allows small and lipid soluble molecules to pass freely but is impermeable to large or ionized molecules and cells.
A selective barrier between brain blood vessels and brain tissues whose effect is to restrict what may pass from the blood into the brain. Certain compounds readily cross the blood brain barrier. Others are completely blocked.
