Definitions for "Cooperativity"
Phenomenon in which the binding of one ligand molecule to a target molecule promotes the binding of successive ligand molecules. Seen in the assembly of large complexes, as well as in enzymes and receptors composed of multiple allosteric subunits, where it sharpens the response to a ligand.
Property exhibited by some proteins with multiple ligand-binding sites whereby binding of one ligand molecule increases (positive cooperativity) or decreases (negative cooperativity) the binding affinity of successive ligand molecules.
A phenomenon by which the binding of a ligand to one site of a receptor or enzyme alters the affinities of the other sites.