an oral drug used in combination with other agents to treat tuberculosis and Mycobacterium avium complex (MAC) disease. Side effects may include nausea, headache, visual disturbances and joint pain.
Indications: Treatment of MAC infection in combination with other agents; treatment of TB in combination with other agents. Contraindications: Known hypersensitivity, history of optic neuritis. Dosage: 25 mg/kg/day po for one to two months, followed by 15 mg/kg/day. Toxicity: Optic neuritis, rash, gastrointestinal intolerance, hepatotoxicity. Pregnancy category C; teratogenic in animals.