An abnormal, symmetrical chromosome, consisting of either two 'long arms', or two 'short arms'. An isochromosome of a chromosomeâ€(tm)s long arms will contain duplicated genes present on the long arms, and be missing genes from the short arms.
A metacentric chromosome in which the p and q arms are of equal length and the information in each of the two arms is genetically identical (iso = equal).
A type of chromosomal aberration in which one of the arms of a particular chromosome is duplicated because the centromere divides transversely and not longitudinally as normal during cell division. The two arms of an isochromosome are therefore of equal length and contain the same set of genes.
An isochromosome is a chromosome that has lost one of its arms and replaced it with an exact copy of the other arm. This is sometimes seen in some girls with Turner syndrome or in tumor cells.