Definitions for "Lead Compound"
A compound that exhibits pharmacological properties which suggest its value as a starting point for drug development.
A candidate compound identified as the best "hit" (tight binder) after screening of a combinatorial (or other) compound library, that is then taken into further rounds of screening to determine its suitability as a drug.
A peptide or small molecule that optimally modulates the activity of a receptor or other target protein. A successful lead compound becomes a drug candidate for further development.