Definitions for "Pleiotropy"
Related Terms:
Genetic heterogeneity, Polygenic, Phenocopy, Dominant, Autosomal dominant, Autosomal recessive, Heterozygous, Recessive inheritance, Complex trait, Heterozygote, Recessive, Heterozygosity, Alleles, Dominance, Codominance, Polygene, Dominant inheritance, Homozygous, Incomplete dominance, Autosomal dominant inheritance, Expressivity, Recessive gene, Monohybrid, Dihybrid, Recessive allele, Dihybrid cross, Multifactorial inheritance, Mendelian inheritance, Homozygote, Autosomal recessive inheritance, Congenic, Penetrance, Overdominance, Dominant gene, Codominant, Monohybrid cross, Heredity, Allele, Mendelian, Genotype, Homozygosity, Dominant allele, Haploinsufficiency, Recessive trait, Polygenic inheritance, Fixation, Hybrid vigor, Phenotype, Epistasis, Incomplete penetrance
The side-effect of a mutation that affects a primary trait or function on a secondary trait or function.
property of some genes that, when altered, can effect more than one phenotype.
When a single gene has a role in several processes.
The phenomenon of variable phenotypes for a number of distinct and seemingly unrelated phenotypic effects.
The capacity of different alleles of a gene to affect more than one aspect of a phenotype.
Multiple, apparently unrelated phenotypic effects of mutation at a single gene.
The phenomenon whereby a single mutation affects several apparently unrelated aspects of the phenotype.
The ability of a single allele to have more than one distinguishable effect. The most familiar example is the allele responsible for color pattern in Siamese cats.
(plee´ a tro pee) [Gr. pleion: more] • The determination of more than one character by a single gene.
The multiple effects genes can have (intended and unintended).
Situation under which a gene may influences multiple phenotypes (i.e., there is no 1:1 correspondence between gene and behavior)
The effect of a single gene on more than one trait.
Multiple, often seemingly unrelated, physical effects caused by a single altered gene or pair of altered genes
A phenomenon whereby a particular gene affects multiple traits.
One gene that causes many different physical traits such as multiple disease symptoms.
the phenomenon where a single gene is responsible for a number of distinct and seemingly unrelated phenotypic effects
one gene leading to many different phenotypic expressions. An excellent example of a gene with pleiotropic effects is the gene for myotonic dystrophy. Affected individuals can have one or more of a range of signs and symptoms including characteristic Christmas-tree like cataracts, myotonia, narcolepsy, testicular atrophy, frontal balding, mental retardation, and cardiac abnormalities, among others.
Pleiotropy occurs when a single gene influences multiple phenotypic traits. Consequently, a new mutation in the gene will have an effect on all traits simultaneously. This can become a problem when selection on one trait favours one specific mutant, while the selection at the other trait favours another mutant.