Definitions for "Tamoxifen"
a chemical compound (C26H29NO) which is non-steroidal but physiogically active as an estrogen antagonist. It is used to treat postmenopausal breast cancer. Chemically it is 1-p-dimethylaminoethoxyphenyl-trans-1,2-diphenyl-but-1-ene. It can be obtained as a white crystalline powder.
Hormone treatment for breast cancer. Stops breast cancer cells from picking up Oestrogen. Oestrogen can encourage breast cancer to grow.
One of the designer estrogen drugs (SERMs). Used in breast cancer patients to prevent recurrence; being considered for breast cancer prevention in high-risk women because of anti-estrogen effect in the breast. (Also see raloxifene and designer estrogens)
An antihormonal agent, that has been investigated alone and with other chemotherapy agents for the treatment of metastatic melanoma and found not to add benefit.