A type of drug that lowers LDL (“bad” cholesterol) by inhibiting HMG CoA reductase, the enzyme that manages the rate of cholesterol production. Statin drugs also enhance the capability of the liver to remove LDL-cholesterol already in the blood.
A class of drugs used to lower cholesterol. Statins inhibit the liver enzyme hMG CoA reductase, which is used in the manufacture of cholesterol. Statins include lovastatin (Mevacor), pravastatin (Pravachol), simvastatin (Zocor), fluvastatin (Lescol), and atorvastatin (Lipitor).
A class of drugs that are usually the first-line choice for lowering high LDL cholesterol. These drugs work by reducing the amount of cholesterol produced by the liver, which triggers liver cells to absorb more cholesterol from the bloodstream. Statins have been shown to reduce the risk of heart attack, stroke, angina, and arrhythmia in many ways. They have powerful antioxidant and anti-inflammatory effects.
are a class of drugs that are effective for lowering LDL cholesterol, lowering TG and raising HDL levels and are generally well tolerated. The statins currently available include atorvastatin, fluvastatin, lovastatin, pravastatin and simvastatin.
A drug class (called HMG-CoA reductase inhibitors) that may help reduce levels of LDL ("bad cholesterol") in the blood. Often prescribed to patients with high cholesterol levels who have a history of heart attack or who are at risk.
A family of medications (HMG-CoA reductase inhibitors) that suppress the production of LDL while increasing the number of receptors in the liver that take in and destroy LDL cholesterol. Statins are among the most effective cholesterol-lowering drugs currently on the market, but they have been associated with potential liver problems, so liver function must be monitored regularly.
Drugs that interfere with the manufacture of cholesterol by the liver and are used to treat high blood cholesterol levels. Because statins may also promote reabsorption of cholesterol deposits in the arteries, they are being studied as a possible means to reverse atherosclerosis. Cholesterol lowering by statins (e.g., pravastatin, atorvastatin, simvastatin) has been a major breakthrough, slowing the progression of atherosclerosis and reducing heart attack and sudden death. They also decrease the frequency of angina pectoris.
Drugs which inhibit the action of the enzyme HMG-CoA reductase, blocking the manufacture of cholesterol in the body, mainly the liver. They are considered the gold standard therapy and are the most widely prescribed lipid-modifying drugs.
Cholesterol-lowering medications that interfere with the enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase; also known as HMG-CoA reductase inhibitors. Statins work by changing the way the liver processes lipids (see Cardiovascular Health).