a hypotensive tissue hormone (C50H73N15O11) which acts on smooth muscle, dilates peripheral vessels and increases capillary permeability. It is formed locally in injured tissue and is believed to play a role in the inflammatory process. It is a nonapeptide with the sequence: Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg.
Chain of nine amino acids; it is a powerful vasodilator that causes increased permeability. It constricts smooth muscle and stimulates pain receptors.
Large peptide formed by the action of proteases on kininogens that exerts an effect on blood vessels. Bradykinin is a very potent vasodilator and increases permeability of small vessels. It also causes spasms in some smooth muscles, generating pain.
A plasma polypeptide that tends to lower blood pressure and increase capillary permeability.
Bradykinin is a protein found in blood plasma which has a powerful influence in dilating or relaxing the blood vessels, thereby decreasing blood pressure, but also having protective properties on the vessel walls.
Small peptide formed by cleavage from plasma protein with vasodilator actions on arterioles. Also stimulates nociceptors.
Produced from bradykinogen under direction of the enzyme kallikren; bradykinin is an endothelium-derived substance/hormone that causes vasodilation and release of nitric oxide and prostacyclin
One of a group of small proteins that actively affect smooth muscle contraction in blood vessel walls, and so have effects on blood pressure. Bradykinin dilates blood vessels, and also stimulates pain receptors.
A naturally occurring substance which, when present in the blood, causes contractions of smooth muscles, dilates blood vessels, and increases the ability of fluids and molecules to get through blood vessel walls.
A small protein that relaxes the smooth muscle in blood vessel walls and activates pain receptors.
A vasoactive nonapeptide which is the most important mediator generated by the kinin system.
Bradykinin is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids.