Familial Adenomatous Polyposis. (fa-MIL-yul pah-li-PO-sis) An inherited condition in which numerous polyps (tissue masses) develop on the inside walls of the colon and rectum. This condition increases a person's risk of developing colorectal cancer.
Familial adenomatous polyposis. asyndrome in which a gene mutation that influences the development of colon, rectal, and other cancers is inherited. People with FAP usually have hundreds, and sometimes thousands of pre-cancerous polyps, or growths developing at a very early age. FAP is defined as the presence of more than 100 benign (adenomatous) polyps in the large intestine at one examination. Some people with FAP with a mild version of the disease have less than 100 adenomas; in these individuals the diagnosis is made by family history, or by finding the mutation during genetic testing.
An inherited disorder of the gastrointestinal tract in which there are usually 100 or more precancerous polyps.
(fa- mil-e-uhl ad-ehn- NO-mah-tus pa-lee-po-sis): an inherited condition that is a risk factor for developing colorectal cancer at a young age. People with this syndrome develop polyps in the colon and rectum. Usually one or more of these polyps becomes cancerous if preventive surgery is not done. This is due to changes in the APC gene. See also APC gene.
familial adenomatous polyposis. FAP is a condition in which the tendency to develop polyps is inherited. People with this condition generally develop hundreds to thousands of polyps throughout the colon at a young age, usually as teenager or a young adult.
Familial adenomatous polyposis. A rare genetic disorder of the intestines characterized by "carpet-like" growths of polyps that develop along the inner walls of the colon. These areas of abnormal growth typically develop at a relatively young age.
Familial adenomatous polyposis. People who have inherited the FAP syndrome usually develop up to thousands of colon polyps at a young age, as early as their teens; the polyps are benign but some become cancerous over time, and many FAP patients develop colon cancer before they are 40.
An inherited condition in which numerous polyps (growths that protrude from mucous membranes) form on the inside walls of the colon and rectum. It increases the risk for colon cancer. Also called familial adenomatous polyposis or familial polyposis.
Familial Adenomatous Polyposis. An inherited disorder of the gastrointestinal tract in which there are hundreds to thousands of precancerous polyps, usually caused by an inherited mutated copy of the Apc gene.
familial adenomatous polyposis. (fa-MEEL-ee-ul a-deh-NO-meh-tes pah-luh-PO-sis) ( listen) Genetic disease with numerous precancerous polyps in the colon and rectum. Also called familial polyposis.
Familial Adenomatous Polyposis. A rare disease that causes lots of benign polyps (small growths that are not cancerous) to grow in the bowel. People with FAP have an increased risk of getting bowel cancer.
Familial adenomatous polyposis. A hereditary condition that is a risk factor for colorectal cancer. People with this syndrome typically develop hundreds of polyps in the colon and rectum at an early age. Usually 1 or more of these polyps becomes cancerous if preventive surgery is not done.
Familial Adenomatous Polyposis. An inherited condition resulting in the formation of thousands of polyps within the colon, often before age 20.
Familial adenomatous polyposis. An autosomal dominantly inherited predisposition to multiple adenomatous polyps of the colon and a risk for colorectal cancer that approaches 100% by age 60. The germ-line mutation for this disease is the APC gene, which stands for adenomatous polyposis coli. Other cancers, including papillary thyroid carcinoma, periampullary carcinoma, gastric cancer (particularly in FAP patients in Japan), small bowel cancer, pancreatic cancer, sarcomas and brain tumors, as well as desmoid tumors (which are not cancer) complicate this disease.
Familial adenomatous polyposis. An inherited condition in which numerous polyps (growths that protrude from mucous membranes) form on the inside walls of the colon and rectum. It increases the risk of colorectal cancer. Also called familial polyposis.
Familial adenomatous polyposis, a prominent hereditary colon cancer syndrome.