Definitions for "Histiocytosis"
A disease in which histiocytes are the principal cells involved. Langerhans cell histiocytosis is a neoplastic proliferation of histiocytes that involves the skin, bone, brain and other organs.
(Multiple sites) Rapidly progressive malignant cancer infiltrating many parts of body, often including the lungs, liver, spleen, and central nervous system. Special Diagnostics: radiograph and biopsy.
abnormal appearance of histiocytes in the blood. (Histiocytes are produced by the bone marrow and are normally immobile until stimulated by inflammation. They are a type of antigen presenting cell.) cutaneous – benign proliferation of nodules in or under the skin malignant – a rapidly invasive proliferation of neoplastic (new growth) histiocytes. No known treatment, always fatal. systemic – proliferation of histiocytes invading the skin and lymph nodes. Can go into remission for years, or progress to the malignant form. Can be treated, but not cured.