A pigment inclusion in aging nerve cells that is of unknown significance.
A naturally occurring lipid pigment with histochemical characteristics similar to ceroid. It accumulates in various normal tissues and apparently increases in quantity with age.
A pale yellow-brown pigment that stains red with Sudan black and is PAS-positive. Lipofuscin granules accumulate in the cytoplasm of muscle and nerve cells, acting as a marker of wear and tear. They increase normally with age or pathologically in certain conditions such as Alzheimer's disease, parkinsonism and certain lysosomal diseases.
Also called lipofuscin] The brown-colored material made of free-radical-damaged protein and fat that concentrates beneath the skin, in the muscles including the heart. It is found in the liver and other vital organs. Lipofuscin is particularly troublesome in brain tissue where it accumulates over a lifetime. In the brain, when the lipofuscin finally reaches a critical level in a neuron, the neuron dies.
Brown wear and tear pigment found in autophagic vacuoles.
Fatty deposits in the retina which are thought to be toxic to retinal cells - by p product of drusen
the brown waste material deposited in skin and nerve cells that is commonly called “age spots.” Lipofuscin is made of free radical damaged proteins and fats.
a yellow-brown pigmented waste material deposited in many nerve and skin cells, where it is believed to interfere with cellular metabolism. Lipofuscin is made up of cross-linked, peroxidized lipids and cross-linked proteins. Lipofuscin deposits in skin are colloquially called "age spots" or "liver spots".
Amber or brown pigment sometimes found in older cells
Lipofuscin is the name given to brown pigment granules composed of lipid-containing residues of lysosomal digestion. It is considered one of the aging or "wear and tear" pigments; found in the liver, kidney, heart muscle, adrenals, nerve cells, and ganglion cells. "Liver spots" commonly associated with aging are superficial dermal lipofuscin deposits.
