Mast cells are uniquely rich in chemical mediators that when released, either as a result of an allergic reaction or for any reason, can cause edema, itching, bronchospasm, and inflammation. They line the mucous membranes of the bronchial tubes, respiratory mucosa of eyes, nose, sinus, and intestinal tract. The skin is also rich in mast cells. The mast cells have special receptors for IgE and play central role in allergic reactions and asthma.
Type of tissue cells which have a high histamine content and which participate in allergic reactions in the process called mast cell degranulation.
Typically found in connective tissue, mast cells can be provoked by antigens or inflammation to release histamine.
Part of connective tissue.
white blood cells containing granules of chemicals including histamine, important in inflammatory responses.
cells found distributed near blood vessels in most tissues, that are full of granules containing inflammatory mediators. Tissue cell that releases histamine and other chemicals involved in inflammation.
large granule-containing cells
Cells present close to body surfaces (such as the skin and intestines), which produce and release chemicals-for instance, histamine-which then produce allergic symptoms
"Guard" cells in skin, mucosal membranes, etc. Initiate inflammatory reactions when they are reached by an agent which is perceived as alien to the body. Are prepared for this by antibodies located on their surface (antennae). When these recognize the foreign matter the mast cell releases histamine, and other signal substances, and cytokines (see above).
Cells involved in the immune response and that play a role in allergy by releasing substances that lead to symptoms such as runny nose and mucus production. Mast cells contain packets of chemicals (eg, histamine) responsible for the symptoms of allergy.
Special cells of the immune system that carry antibodies and release histamine when the matching antigen binds. Mast cells are abundant in 'exposed' tissues such as the respiratory tract
Cells that synthesize and release histamine, as during an allergic response; found most often in connective tissue surrounding blood vessels.
Mast cells play an important role in the body's allergic response. Mast cells are present in most body tissues, but are particularly numerous in connective tissue, such as the dermis (innermost layer) of skin. In an allergic response, an allergen stimulates the release of antibodies, which attach themselves to mast cells. Following subsequent allergen exposure, the mast cells release substances such as histamine (a chemical responsible for allergic symptoms) into the tissue.
cells, which synthesize and store histamines, found in most body tissues, particularly just below the epithelial surfaces, serous cavities and around blood vessels. In an allergic response, an allergen stimulates the release of antibodies, which attach themselves to mast cells.
cells which contain histamine-filled granules and which patrol the body's tissues, playing an important role in allergic reactions.
Tissue cells which when connected to immunoglobulin E antibodies release histamine or other substances causing allergic symptoms.
Cells found in gastrointestinal tract and skin. They contain histamines and play a vital role in inflammation and allergy
granulated cells that found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the basophils, mast cells contain large amounts of histamine and heparin. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the stem cell factor. Source: http://ghr.nlm.nih.gov/ghr/glossary/mastcells
Histamine-releasing cells in case of allergic reaction.
The cells that release histamine during an allergic reaction after being triggered by IgE.
Connective tissue cell with granules which contain heparin and histamine
Cells found distributed near blood vessels in most tissues. These cells are full of granules containing inflammatory mediators.