Definitions for "Tumor Necrosis Factor"
a monokine produced in various parts of the body. It is important in stimulating leukocytosis, fever and necrosis (death of some tissues surrounded by healthy tissue). This might be described as the body's natural form of chemotherapy.
a protein in the body involved in inflammatory processes. When overproduced in the body, it also damages tissue in and around the joints of people with psoriatic arthritis.
a macrophage/monocyte-derived cytokine that mediates tumor cell necrosis.
An experimental immunotherapy being investigated as an agent in isolated limb perfusion.