Definitions for "Microsatellite"
Related Terms:
Short tandem repeat, Str, Repetitive dna, Transposon, Rapd, Restriction fragment length polymorphism, Rflp, Replicon, Genomic dna, Cosmid, Markers, Pseudogene, Yac , Insertion, Vntr, Shotgun sequencing, Cloning vector, Homeobox, Polymerase chain reaction, Bac, Recombinant dna technology, Homologous recombination, Bacterial artificial chromosome, Molecular marker, Pseudogenes, Recombinant dna, Restriction fragment, Marker, Dna sequence, Gene cloning, Expressed sequence tag, Exons, Plasmid, Amplification, Gene splicing, Expression vector, Trinucleotide repeat, Plasmids, Transposition, Gene targeting, Est, Contigs, Cpg island, Homeotic gene, Yeast artificial chromosome, Okazaki fragment, Marker gene, Transposase, Sequencer, Rdna
A repetitive stretch of short DNA sequences that occur in increased numbers in cancer cells.
A class of repetitive DNA sequences that are made up of tandemly organized repeats that are 2-8 nucleotides in length. They can be highly polymorphic and are frequently used as molecular markers in population genetics studies.
A type of genetic marker that consists of numerous repeats of short sequences of DNA bases. Microsatellites are currently the marker of choice for population studies, selective breeding, etc., because they are found at loci throughout the animal’s DNA and have a likelihood of being highly polymorphic (see below).
Repetitive stretches of short sequences of DNA used as genetic markers to track inheritance in families.
Short DNA sequences of di-or trinucleotide repeats of variable length distributed widely throughout the genome.
A type of simple sequence length polymorphism comprising tandem copies of, usually, di-, tri- or tetranucleotide repeat units.
A class of repetitive elements randomly distributed in the genome where motifs of one to six nucleotides are tandemly repeated.
Short repeats of genomic sequences of nucleotides that are repeated in multiple tandem copies.
a short, DNA sequence (a Tandemly Repetitive DNA sequence) that is repeated many times within
a simple sequence repeat (SSR)
a small, repetitive sequence (such as AAAAA, GTGTGT, CAGCAGCAG)
Microsatellites are repeated sections of DNA, two to five base-pairs in length, found scattered throughout the human genome. Because they are highly variable, microsatellites are often used in genetic studies, and in forensic and paternity tests.
(synonyms: satellite DNA, short tandem repeats) Repetitive segments of DNA two to five nucleotides in length (dinucleotide/trinucleotide/tetranucleotide/pentanucleotid e repeats), scattered throughout the genome in non-coding regions between genes or within genes (introns), often used as markers for linkage analysis because of the naturally occurring high variability in repeat number between individuals. These regions are inherently unstable and susceptible to mutations.
A type of DNA polymorphism which involves very small repeating units such as dinucleotides.
A very short unit sequence of DNA (2 to 4 bp) that is repeated multiple times in tandem. Microsatellites (also called Simple Sequence Repeats or SSRs) are highly polymorphic and make ideal markers for linkage analysis (see Chapter 8). A polymorphism at a microsatellite locus is also referred to as a Simple Sequence Length Polymorphism (SSLP).
DNA sequences composed of a tandem repetition of a simple short sequence (frequently a dinucleotide), occurring in the genome of many higher organisms.
A class of repetitive DNA. Microsatellites are simple sequence repeats one to eight nucleotides in length. For example, the repeat unit can be simply "CA", and might exist in a tandem array (CACACACACA) 50 or more repeat units in length. The number of repeats in an array can be highly polymorphic
Another term for "STR" - A repeat of genetic material at a specific location.
A special region of DNA which possesses an unusual base sequence where two, three or four bases are repeated over and over again, for example CACACACA etc or GCGCGCGC etc. these microsatellites have proved to be very useful markers in developing the canine genetic map.
Tract of DNA consisting of a specific short sequence repeated many times. The number of repeats in each microsatellite varies widely among different individuals. Most microsatellites are not within genes.
See short tandem repeat.
As used here, a region of the DNA that can be consistently identified, using a laboratory procedure, across all individuals in a single breed. Microsatellites themselves are repetitive DNA sequences that are randomly distributed throughout the mammalian genome, tend to be highly polymorphic, and are short DNA segments.
See STR.
Tandem repeat of generally 2-4 bases. Used as genetic markers as repeat units variable
Repetitive stretches of short DNA sequences that are used as markers to track the inheritance of genes.
A short sequence of DNA, usually 1 to 4 basepairs (a unit of DNA), that is repeated together in a row along the DNA molecule. There is variation from person to person in the number of repeats. There are hundreds of places in human DNA that contain microsatellites.
a specific sequence of DNA bases or nucleotides which contains mono, di, tri, or tetra tandem repeats. For example GGGGGGGG is a (G)8 ACACAC is referred to as a (AC)4 ATCATCACTACTACT would be referred to as (ATC)5 ATCTATCT would be referred to as (ATCT)2 Microsatallites also are called simple sequence repeats (SSR), short tandem repeats (STR), or variable number tandem repeats (VNTR).