A disease characterized by deposition of fibrous tissue in skin and internal organs.

Widespread connective tissue disease in which skin and other body parts gradually degenerate, thicken and become stiff. See Connective tissue disease.

A connective tissue disorder affecting primarily the skin, oesophagus and heart.

is a progressive systemic disorder with associated thickening and tightening of the skin, especially on the arms, face, and hands, and resulting loss of flexibility.

An immune disorder affecting many parts of the body including particularly the skin and the intestine.

A chronic, autoimmune disease of the connective tissue generally classified as one of the rheumatic diseases; also known as systemic sclerosis. Scleroderma is a condition in which the symptoms may either be visible, as when the skin is affected, or invisible, as when only internal organs are involved. It is a highly individualized disease; involvement may range from mild symptoms to life threatening.

A chronic disease characterized by hardening or thickening of the skin due to abnormal tissue growth.

A disease of the skin and connective tissue that causes the skin to become hard and can result in hair loss.

an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin

genus of poisonous fungi having hard-skinned fruiting bodies: false truffles

an autoimmune connective tissue disease characterized by cutaneous thickening due to changes in the dermal connective tissue

A disease of the connective tissues and blood vessels that leads to hardening of the skin. Scleroderma can also damage internal organs such as the kidneys, lungs, heart, or gastrointestinal tract.

A disease that can affect the joints, skin, internal organs and blood vessels.

A chronic disorder marked by hardening and thickening of the skin. Scleroderma can be localized or it can affect the entire body (systemic).

Dermatosclerosis; hide-bound or skinbound disease; thickening of the skin caused by swelling and thickening of fibrous tissue, with eventual atrophy of the epidermis (skin layer); a manifestation of progressive systemic sclerosis.

autoimmune disease of connective tissue characterized by excessive collagen deposition in the skin and internal organs; found mostly in women.

A chronic disease characterized by degenerative changes and scarring in the skin, joints, and internal organs and by blood vessel abnormalities. Often mistaken as Buerger's Disease.

A potentially fatal disease, occuring primarily in women, caused by excessive production of collagen in the connective tissue.

A chronic disease that most often strikes women during middle age. It can cause hardening and thickening of the skin and, in its most severe form, attack the heart, lungs, kidneys and gastrointestinal tract. Scleroderma, which literally means "hard skin," is caused by an overproduction of collagen in your body's connective tissue. Collagen is normally responsible for keeping your skin and organs supple, but when it is overproduced, it makes tissue thick and immobile.

a very serious disease of the body's connective tissue that causes thickening and hardening of the skin.

Scleroderma (also known as sclerosis) is a rare, autoimmune, connective tissue disease characterised by abnormal thickening of the skin. It primarily affects women aged 30-50 years.

A chronic condition that can cause thickening or hardening of the skin.

Thickening of the skin, caused by swelling and thickening of fibrous tissue, that results in eventual atrophy of the epidermis. Scleroderma frequently affects esophageal muscle function.

An autoimmune disease characterized by abnormal growth of connective tissue in the skin and blood vessels. In more severe forms, connective tissue can build up in the kidneys, lungs, heart, and gastrointestinal tract, leading in some cases to organ failure.

Scleroderma is an autoimmune disorder marked by hardening of the body's connective tissue, but can also involve internal organs such as the heart, lungs, kidneys and the gastrointestinal tract. There are two types of scleroderma: CREST, which is limited to the skin, and progressive systemic sclerosis, which affects internal organs. (See CREST and Progressive systemic sclerosis)

An autoimmune disease which largely attacks elastin (an important protein in connective tissue that allows for elasticity of muscles and skin). Scleroderma can attack potentially every part of the body and is noted for its outward effects on the skin.

chronic, degenerative disease that affects the joints, skin, and internal organs.

a connective tissue disorder causing hardening of the skin and other organs

Persistent hardening of any of the body’s connective tissue.

Scleroderma is a chronic inflammatory connective tissue disease characterised by tightening and thickening of the skin throughout the body or limited to the limbs. Mostly it is preceded by Raynaud's phenomenon (the extremities turn white). Systemic sclerosis is a more generalised form with involvement of organs (oesophagus, kidneys, lungs) resulting in swallowing difficulties, high blood pressure and shortness of breath. Read also our page on scleroderma.

A disease of connective tissue with the formation of scar tissue (fibrosis) in the skin and sometimes also in other organs of the body. See the entire definition of Scleroderma

an autoimmune disease in which the skin thickens and hardens; sometimes other parts of the body are affected and joint pain may result

A disease in which the skin becomes progressively hard and thickened.

A disease of the skin and connective tissue that can cause hair loss over the affected areas.

an autoimmune disease of connective tissue, characterized by the formation of scar tissue (fibrosis) in the skin and organs of the body leading to thickness and firmness of involved areas; systemic sclerosis

The Condition"...The systemic forms of scleroderma cause fibrosis ( scar tissue) to be formed in the skin and/or internal organs..." Related Topic"An autoimmune disease of the connective tissue, characterized by the formation of scar tissue (fibrosis) in the skin and organs of the body..."

Scleroderma is a rare, chronic disease characterized by excessive deposits of collagen in the skin or other organs. Progressive systemic scleroderma or systemic sclerosis, the generalised type of the disease, can be fatal. The localised type of the disease tends not to be fatal.