Definitions for "achondroplasia"
a skeletal disorder beginning before birth; cartilage is converted to bone resulting in dwarfism.
short limb skeletal dysplasia, due to a mutation in a dominant gene encoding fibroblast growth factor receptor-3 (FGFR3). Most common limb dysplasia, with shortened long bones (mainly proximal long bones) and is difficult to prenatally diagnose. Other mutaions of this gene cause milder skeletal dysplasia (hypochondroplasia) and a lethal skeletal dysplasia (thanatophoric dysplasia). (More? Musculoskeletal Abnormalities | OMIM Achondroplasia | FGFR3)
Improper development of cartilage at the ends of the long bones, resulting in a form of congenital dwarfism. A defect in most breeds and a requisite in others like Dachshunds and Basset Hounds.