A craniofacial abnormality characterized by an abnormal head shape, small upper jaw, and fusion of the fingers and toes.

Rare genetic disorder which is apparent at birth. The syndrome is characterized by skeletal and associated skull malformations of the head, face, hands, and feet.

Apert Syndrome, virtually synonymous with Acrocephalosyndactyly, is a branchial arch syndrome, resulting from a developmental anomaly. Specifically, this syndrome affects the first branchial (or pharyngeal) arch, which is the precursor of the maxilla and mandible. Since the branchial arches are important developmental features in a growing embryo, disturbances in its development create lasting and widespread effects.