A semipermeable membrane that controls diffusion of molecules into the cerebrospinal fluid.

Referring to a property of blood vessel cells in the central nervous system that keeps certain substances from entering the brain tissue.

Protective membrane that separates circulating blood from brain cells, making it more difficult for some drugs to pass into the brain than into the other tissues.

a set of physical barriers between the blood vessels and the brain that allows only certain substances to pass through.

a layer of tightly bound cells that prevents certain substances carried in the bloodstream from entering the brain

The barrier which exists between the blood and the cerebrospinal fluid which prevents the passage of various substances from the bloodstream to the brain.

Capillaries of cerebral circulation have a uniquely restricted permeability to larger non-lipid molecules. Not present in specific areas. Structurally made up of investing glial cells.

A selectively permeable, protective barrier that limits the passage of substances in the bloodstream into brain tissue. It is believed to be formed by astrocytes and blood vessels.

Specialized membranes that surround the blood vessels within the brain and that filter toxins and other harmful chemicals, ensuring brain cells' a relatively pure blood supply.

A blockade consisting of cells and small blood vessels that limits the movement of substances from the bloodstream into the brain.

A property of the blood vessels of the brain that prevents most chemicals from diffusing from the blood into the brain.

is formed by the very high resistance tight junctions between the cerebral capillary endothelial cells, which are maintained in this state by astrocytes. The BBB serves to prevent the passage of large molecules and cells into the CNS

a protective layer that prevents many ions and compounds of large molecular weight passing from the blood to brain tissue.

A network of blood vessels with closely spaced cells that prevents many substances from leaving the blood to cross the capillary system into the brain tissue.

A mechanism involving the capillaries and certain other cells of the brain that keeps many substances, especially water-based substances, from passing out of the blood vessels to be absorbed by the brain tissue.

system for preventing toxin entry into CNS See also: astrocyte, vasculitis

the membrane that seperates the blood from brain cells.

A network of blood vessels located around the central nervous system with very closely spaced cells that make it difficult for potentially toxic substances-including anticancer drugs-to penetrate the blood vessel walls and enter the spinal cord.

A functional concept to explain the observation that many substances transported by blood readily enter other tissues, but do not enter the brain. The barrier functions as if it were a continuous membrane lining the brain vasculature.

a mechanism that creates a barrier between brain tissues and circulating blood; serves to protect the central nervous system; "the brain was protected from the large molecules of the virus by the blood-brain barrier"

A system [inhibits] substances in the bloodstream […] from entering the nervous system” ( Levinthal, 64).

The division between the blood circulation and the tissue of the brain, which is permeable only to specific molecules, always below a certain size

Close knit cells of blood vessels in the brain, which limit substances that can enter the brain. 635

A thin layer of tightly packed cells separating the central nervous system from the body's blood stream. This layer blocks the ability of many substances, including certain drugs, from entering the brain.

An anatomical-physiological feature of the brain that consists of special cells which line the walls of the blood vessels in the brain. These cells are called "endothelial cells." The barrier separates the parenchyma of the central nervous system from blood. The blood-brain barrier functions in preventing or slowing the passage of various chemical compounds, radioactive ions, and disease-causing organisms, such as viruses, from the blood into the central nervous system.

Functional barrier produced by glial cells wrapped around blood vessels preventing access of many blood-borne molecules to the brain.

A semipermeable membrane that keeps the blood that is circulating in the brain away from the tissue fluids surrounding the brain cells.

A semi-permeable layer around blood vessels in the brain and spinal cord that prevents large molecules, immune cells, and potentially damaging substances and disease-causing organisms (such as viruses) from passing out of the blood stream into the central nervous system (brain and spinal cord). A break in the blood-brain barrier may underlie the disease process in MS.

A protective network of blood vessels and cells that filters blood flowing to the brain.

A barrier created by brain capillaries that prevents many substances from leaving the blood and crossing the capillary walls into the brain tissues. Certain compounds can readily cross the blood-brain barrier; others can not.

made of specialized brain capillaries and astrocytes (brain cells that attach nerve to blood vessels) that prevent passage of materials from blood to cerebrospinal fluid and the brain

the protective membrane that separates circulating blood from brain cells.

A microscopic meshwork that prevents many substances circulating in the bloodstream from entering the brain.

a membrane that that prevents harmful substances crossing over from the blood circulation to the tissues of the brain.

the protective membrane that separates the bloodstream from brain tissue

a membrane separating brain tissue from circulating blood. In HIV treatment, it usually refers to the difficulty of getting drugs from the blood stream to penetrate into the central nervous system. HIV is active in brain tissue. The drug AZT (zidovudine, Retrovir? crosses the blood-brain barrier better than any other anti-HIV drug currently approved in the United States.

The protective membrane that separates circulating blood from the brain

filter that allows only certain materials to cross from the bloodstream to the brain, protecting it from potentially harmful substances; in drug development, this may be an obstacle or a benefit: some drugs are intended to cross the barrier while others are not because they could trigger harmful neural side-effects

A protective barrier formed by the blood vessels and glia of the brain. It prevents some substances in the blood from entering brain tissue.

A type of filter that prevents some substances but not others into the central nervous system (CNS) from the blood stream.

A wall of nerves and cells surrounding the brain membrane. While this barrier has a protective function, it also reduces the ability of chemotherapeutic drugs to effectively reach some brain tumors.

An elaborate network of supportive brain cells, called glia, that surrounds blood vessels and protects neurons from the toxic effects of direct exposure to blood.

Unlike blood vessels in other body parts, blood vessels in the brain have developed an additional barrier mechanism to protect the brain from potentially harmful chemical substances in the blood.

a group of mechanisms that keep some substances in the bloodstream from entering cells in the brain.

A barrier consisting of specialized brain capillaries and astrocytes that prevents the passage of materials from the blood to the cerebrospinal fluid in the brain.

A group of cells that form a special, impermeable lining in the blood vessels of the brain. The blood-brain barrier is made up of astrocytes and prevents toxic substances in the blood from entering the brain.

Protects the brain from the entry of many substances. In MS, it fails to keep out activated T cells.

A network of tightly packed cells in the walls of capillaries in the brain that prevents many molecules, including poisons, from entering the brain.

Tightly joined cells in the blood vessels of the brain that prevent the ready diffusion of substances into the brain tissue.

Mechanism that regulates entry of blood into the brain.

The selective barrier that controls the entry of substances from the blood into the brain. rain One of the two components of the central nervous system, the brain is the center of thought and emotion. It is responsible for the coordination and control of bodily activities, and the interpretation of information from the senses (sight, hearing, smell, etc.)

A network of blood vessels with closely spaced cells that makes it difficult for potentially toxic substances (such as anticancer drugs) to penetrate the blood vessel walls and to enter the brain.

protects the brain from chemical intrusion from the rest of the body. Blood flowing into the brain is filtered so that many harmful chemicals cannot enter the brain.

The blood-brain barrier (abbreviated BBB, not to be confused with the blood-cerebrospinal fluid barrier, a function of the choroid plexus) is a membrane that controls the passage of substances from the blood into the central nervous system. Astrocytes, a type of glial cell specific to the central nervous system, form a tight barrier between the blood capillaries of the brain and the ependymal cells lining the ventricles of the brain.