Interim Reregistration Eligibility Decision. The United States Environmental Protection Agency (US EPA) issues an IRED for a pesticide that is undergoing reregistration. The IRED, issued after the US EPA completes the individual pesticide's aggregate risk assessment, may include taking risk reduction measures to gain the benefits of these changes before the final Registration Eligibility Decision (RED) can be issued following the US EPA's consideration of cumulative risks. See RED.