An inherited blood disorder affecting the production of hemoglobin.
the absence or reduction of alpha- or beta-chain synthesis in hemoglobin. The homozygous condition (thalassemia major) is characterized by a high frequency of hemoglobin F and fatal anemia; the heterozygous condition (thalassemia minor) is highly variable but usually occurs with mild symptoms.
a group of blood diseases, that are inherited, which affect a person's hemoglobin and cause anemia. Hemoglobin is a protein in red blood cells that carries oxygen and nutrients to cells in the body.