Cells of a single type taken from an animal or human and grown in the laboratory. cohort study - A research study that compares a particular outcome, such as lung cancer, in groups of individuals who are alike in many ways but differ by a certain characteristic - for example, female nurses who smoke compared with those who do not smoke.
Population of cells of plant or animal origin capable of dividing indefinitely in culture.
A population of cultured cells, of plant or animal origin, that has undergone a change allowing the cells to grow indefinitely, in contrast to a cell strain. Cell lines can result from chemical or viral transformation and are said to be immortal.
Cells grown in tissue culture, representing generations of a primary culture.
Cell lines are distinct families of cells grown in culture. Cells in the same line are typically clones. Different cell lines have different characteristics. Cell lines are usually associated with cytotoxicity or intracellular test assays.
A general term applied to a defined population of cells that has been maintained in culture for an extended period and usually has undergone a spontaneous process, called transformation, that allows the cells to continue dividing (replicating) in culture indefinitely.
a cell population derived from a primary culture at the first sub-cultured
a clone of a primary cell that is capable of stable growth in vitro for many generations
a collection of cells that are grown in the laboratory from an original tissue specimen
a culture of a particular type of cell that can reproduce indefinitely
a culture of propagating cells
a culture that arises from an individual explant
a population of cells formed by one or more subcultivations of a primary cell culture
a supposedly genetically uniform population of cells derived from one individual cell, or it could be a clone (theoretically genetically identical descendants) of one original cell
A group of dividing cells derived from abnormal tissue (e.g., a tumor) which are immortal. They have abnormal nuclei and almost always produce tumors when injected into an animal. Example: HeLa cells.
Cells that grow and divide indefinitely outside the body, and are originally derived from one specific cell.
progeny of a prior cell culture which are identical and always cultured further under defined conditions
A population of cells propagated in culture that are totally derived from, and therefore genetically identical to, a single common ancestor cell.
A supposedly genetically uniform population of cells derived from one individual cell. The genetic identity of all the cells is a fiction, as the genetic material is subject to many ‘fluid genome’ processes that constantly make cells genetically different from one another, and especially in culture. Both plant and animal cells are subject to large variations known collectively as somaclonal variations.
Cells that will grow indefinitely in the laboratory given appropriate living conditions.
A continuous growing cell culture that is stable. Usually clonal or derived from a single cell.
The identifier for the immortalized cell line if one was used to derive the BioMaterial [MGED Ontology Definition
Cells of common descent and type cultured in the laboratory.
a specific type of cell that is maintained in vitro for medical and/or research purposes.
(sell line) Permanently established cell culture that will proliferate indefinitely given appropriate fresh medium and space
A stably transformed line of cells that have a high capacity for multiplication in vitro..
cells derived from one individual cell which are supposedly genetically uniform or identical
Cells of a particular type that can be maintained and grown in culture, outside the body in a Petri dish.
A cell line arises from a primary culture at the time of the first successful subculture. The term cell line implies that cultures from it consist of lineages of cells originally present in the primary culture. The terms finite or continuous are used as prefixes if the status of the culture is known. If not, the term line will suffice. The term "continuous line" replaces the term "established line". In any published description of a culture, one must make every attempt to publish the characterization or history of the culture. If such has already been published, a reference to the original publication must be made. In obtaining a culture from another laboratory, the proper designation of the culture, as originally named and described, must be maintained and any deviations in cultivation from the original must be reported in any publication.
Cells of a single type that have been adapted to grow and divide in the laboratory and are used in research.
