A contiguous region of DNA sequence constructed by aligning many sequence "reads" (one "read" is the data generated from one sequencing reaction).
A DNA sequence that overlaps with another contig. The full set of overlapping sequences (contigs) can be put together to obtain the sequence for a long region of DNA that cannot be sequenced in one run in a sequencing assay. Important in genetic mapping at the molecular level.
A length of contiguous sequence assembled from partial, overlapping sequences, generated from a "shotgun" sequencing project. Contigs are typically created computationally, by comparing the overlapping ends of several sequencing reads generated by restriction enzyme digestion of a segment of genomic DNA. The creation of contigs in the presence of sequencing errors, ambiguities and the presence of repeats is one of the most computationally challenging aspects of the role of Bioinformatics in genome analysis.
This is short for contiguous sequence. When two sequences overlap at their ends (known as a "dove-tail" overlap). The sequences can be collapsed into a single, non-redundant sequence. Read more about contigs references: Jang W et al (1999) Making effective use of human genomic sequence data. Trends Genet. 15(7): 284-6. Kent WJ and Haussler D (2001) Assembly of the working draft of the human genome with GigAssembler. Genome Res 11(9): 1541-8. Agarwala R et al (Manuscript in preparation).
A set of DNA fragments that overlap to yield a continuous sequence without gaps.
A stretch of genomic DNA assembled from raw sequence data. The contig lengths vary and may span many genes or only part of a gene. When enough overlapping contigs become available they are assembled into whole chromosome sequences.
The set of ordered overlapping clones in a chromosome/genome.
a continuous stretch of genomic DNA generated by assembling cloned fragments by means of their overlaps
an ordered list of overlapping reads
uous gene syndrome: A constellation of findings caused by a small chromosome deletion or duplication that spans two or more adjacent genes
A set of contiguous overlapping genomic clones that together span a larger region of the genome than that covered by any one clone (see Chapter 7 and Chapter 10). See Contig in the MGI Glossary.
A set of ordered overlapping clones that constitute a chromosomal region or a genome.
Sequences of clones, representing overlapping regions of a gene, presented as an assembly or multiple alignment.
A chromosome map showing the locations of those regions of a chromosome where contiguous DNA segments overlap. Contig maps are important because they provide the ability to study a complete, and often large segment of the genome by examining a series of overlapping clones which then provide an unbroken succession of information about that region.
(Contiguous Map) The alignment of sequence data from large, adjacent regions of the genome to produce a continuous nucleotide sequence across a chromosomal region
a group of BACs or fragments of DNA sequences that represent contiguous, overlapping regions of the genome.
contiguous sequence of DNA created by assembling shorter, overlapping sequenced fragments of a chromosome (whether natural or artificial, as in BACs). A list or diagram showing an ordered arrangement of cloned overlapping fragments that collectively contain the sequence of an originally continuous DNA.
Group of clones representing overlapping regions of a genome.
A group of cloned (copied) pieces of DNA representing overlapping regions of a particular chromosome. A DNA sequence that overlaps with another contig.
In shotgun DNA sequencing projects, a contig (from contiguous) is a set of overlapping DNA segments derived from a single genetic source. A contig in this sense can be used to deduce the original DNA sequence of the source. This meaning of contig is in accordance with the original definition by Staden [1979].
