An enzyme that separates the two DNA strands in a double helix, which results in the formation of regions of single-stranded DNA.
An enzyme that unwinds the double DNA helix near the replication fork before DNA polymerase acts on it. Replication fork moves from 3' to 5' of the leading strand. Unwinding is also necessary for DNA repair. Mutations in the helicase genes on chromosome 2q and 19q are one group of causes of the DNA repair defect xeroderma pigmentosum (an autosomal recessive disease). See also primosome.
an enzyme that unravels the DNA double helix and breaks the hydrogen bonds
an enzyme that uses energy provided by ATP hydrolysis to separate the strands of a nucleic acid duplex
a protein involved in RNA genome replication and virus movement
An enzyme that breaks base pairs in a double-stranded DNA molecule.
an enzyme that unwinds a DNA double helix molecule ahead of DNA polymerase III
An enzyme that makes nucleic acids single stranded by translocating along one strand, powered by ATP hydrolysis.
an enzyme which promotes the unwinding of the DNA strand.
An enzyme that unwinds the double helix of DNA to allow for replication.
Helicases are a class of enzymes vital to all living organisms. They are motor proteins that move directionally along a nucleic acid phosphodiester backbone, separating two annealed nucleic acid strands (i.e. DNA, RNA, or RNA-DNA hybrid) using energy derived from nucleotide hydrolysis.
