Definitions for "Reverse Transcriptase"
A chemical used by HIV to help make copies of itself.
An HIV enzyme that the virus requires to reproduce itself
This enzyme of HIV -- and other retroviruses -- converts the single-stranded viral RNA into DNA, the form in which the cell carries its genes. Some antiviral drugs approved by the FDA for the treatment of HIV infection (e.g., AZT, ddC, ddI, 3TC, D4T, and abacavir) work by interfering with this stage of the viral life cycle. They are also referred to as reverse transcriptase inhibitors (RTIs).