RNA interference is a process initiated by double stranded RNA which inhibits gene expression in a sequence-dependent fashion. This process was recently discovered in human cells and speculations remain as to its physiological meaning. Meanwhile, RNA interference has emerged as a powerful gene silencing technique, useful in research and therapy development.

(RNAi). A technique in which the expression of a gene is inhibited when a double-stranded complementary RNA is introduced into the organism.

A therapeutic approach for a range of genetic disorders where RNAi could be used to selectively turn off the disease gene in a mouse model. Turning off the disease gene in mice corrected neuroanatomical abnormalities and animals treated with RNAi had improved coordination. Even though RNAi can turn down bad genes, these genes are not completely silenced.