Definitions for "Mismatch repair"
DNA constantly has to produce new strands of itself. When this is done incorrectly, there are special genes involved in correcting the mistake. If this is not done, or not done properly, a tumor can grow in the place of normal cells.
When a single base in DNA is changed into a different base, or the wrong base inserted during DNA replication, there is a mismatch in base pairing with the base on the opposite strand. A repair system removes the incorrect base and inserts the proper one for pairing with the opposite strand.
A DNA-repair pathway that removes and replaces nucleotides that have been misrepaired by DNA polymerases during DNA replication.
an essential system for maintaining genetic stability in bacteria and higher eukaryotes