For an analytical method, the closeness of agreement between results of measurements on identical test material where individual measurements are carried under changing conditions such as: analyst, instrumentation, location, conditions of use, time. (after Metrology, 1984)
the closeness of replicate measurements on the same sample, using the same measuring technique, under the same conditions. Reproducibility can be limited by many factors, including instrument or electrode stability, loss of the substance being measured during sample operation and contamination.
The ability of an instrument to duplicate with exactness, measurements of a given value. Usually expressed as a % of span of the instrument.
The precision between two laboratories. It also represents precision of the method under the same operating conditions over a short period of time.
(Repeatability, Reliability): the results of a test or measure are identical or closely similar each time it is conducted. ( Diagnosis)
The closeness of the output reading for the same value of input over a period of time approaching in both directions. It is usually reported as non-reproducibility as a percent of span and includes hysteresis, drift, repeatability and dead band.
Closeness of the agreement between the results of measurements of the same measurand carried out under changed conditions of measurement.
The ability of a test device to produce the same value during repeated measurements in various laboratories which are participating in a collaborative study.
Closeness of agreement between test results obtained under reproducibility conditions (see below). ISO 5725, 1986. RT reproducibility conditions.
The closeness of agreement among repeated measurements of the output for the same value of input made under the same operating conditions over a period of time, approaching from both directions.
Ability of a test to provide consistent results when applied to aliquots of the same sample at different laboratories..
The closeness of agreement among measurements of the same value of the same quantity where the individual measurements are made under different defined conditions, i.e. by different methods or with different measuring instruments.
The variability of a measurement device when measurements are made under different conditions such as with different operators or different measurement devices.
A general term to describe the precision of results generated from multiple runs of a compound (or any homogenous test sample) in an assay. An assay may lack reproducibility because of either high within-run or across-run variability, or because of systematic trend (drift) over time in the response. An assay that is reproducible across runs is one that has variation within acceptable limits and has no material systematic trends.
Reproducibility across labs expresses the precision between laboratories. It is useful for assessing the “transferability” of an assay and/or the validity of comparing results from samples that are run in two or more laboratories.
The degree of agreement between the concentration of an old gas cylinder and a new cylinder. The degree of agreement between the concentration of an old cylinder, used as a standard, and the concentration of a new cylinder, analyzed as an unknown. Agreement between these two gas cylinders verifies that the calibration of the instrument used to make the comparison is still valid and no recalibration is required.
The ability to duplicate entire experiments or complicated analytical methods between investigators or laboratories.
The precision obtained under conditions where independent test results are produced with the same method on identical test material in different laboratories with different operators using different equipment.
the results of a test or measure are identical or closely similar each time it is conducted. ( Diagnosis) Keyword(s): Repeatability Reliability
Reproducibility is one of the main principles of the scientific method, and refers to the ability of a test or experiment to be accurately reproduced, or replicated, by someone else working independently. The term is very closely related to the concept of testability and, depending on the particular field, may require the test or experiment to be falsifiable.
