A major family of white blood cells that are produced in the bone marrow and circulate in the bloodstream. They are one of the immune system's weapons in attacking and invading organisms, through their production of antibodies.
B-lymphocytes are blood cells of the immune system derived from the bone marrow and spleen involved in the production of antibodies. B-lymphocytes float through all body fluids, are able to detect the presence of foreign invaders, and produce antibodies on their own and when primed by T-lymphocytes. B-lymphocytes can later differentiate into plasma and memory cells. B-cells mediate the "humoral" immune response.
Sub-group of the lymphocytes that mature in the bone marrow, the lymph glands, the spleen and in other lymph organs in humans. Upon contact with a specific antigen, B-lymphocytes develop into antibody-producing plasma cells or into so-called memory cells. The latter again become active upon renewed contact with the same antigen (with the help of the T-lymphocytes) and forward the information stored to the plasma cells that then form specific antibodies ( Specific defence system).