lysis of bone caused by disease or infection or inadequate blood supply 
                                                            
                                                     
                        
                                                
                        
                        
                            The dissolution of bone as a result of a pathological process
                                                            
                                                     
                        
                                                
                        
                        
                            The softening and destruction of bone.
                                                            
                                                     
                        
                                                
                        
                        
                            Destruction of bone caused by disease, infection, or loss of blood supply
                                                            
                                                     
                        
                                                
                        
                        
                        
                                                
                        
                        
                            The dissolution, or disintegration, of bone.
                                                            
                                                     
                        
                                                
                        
                        
                            A dissolution of the organic matrix of bone resulting in destruction.
                                                            
                                                     
                        
                                                
                        
                        
                            Place in the bone at which bone substance is reduced. With multiple myeloma/plasmacytoma, this reduction occurs as a result of excessive activity of the osteoclasts.
                                                            
                                                     
                        
                                                
                        
                        
                            Osteolysis refers to an active resorption or dissolution of bone tissue as part of an ongoing disease process.