A rare disease that occurs more frequently in men than women. It is characterized by anemia, bleeding, recurrent infections and weakness. Ordinarily, it is regarded as a form of cancer that originates in bone marrow and involves mainly the bones.
Malignancy beginning in the plasma cells of the bone marrow. Plasma cells normally produce antibodies to help destroy germs and protect against infection. With myeloma, this function becomes impaired, and the body cannot deal effectively with infection.
cancer caused by uncontrolled proliferation of the white blood cells called plasma cells within the bone marrow. The malignant cells do not usually accumulate in the blood and the tumour growth is restricted to the bones. This leads to bone destruction and is often associated with kidney problems.
a malignancy of plasma cells occurring in the bone marrow and other sites. Multiple myeloma presents in a variety of ways, but has a number of characteristic features including bone destruction with bone pain, anemia, and impaired kidney function.
Disseminated malignancy of B cells of immune system characterized by multiple bone marrow tumors associated with bone pain, pathologic fracture, excess calcium, and anemia. Depression of immunoglobulin level results in susceptibility to infection.
Cancer that affects plasma cells. The disease causes the growth of tumors in many bones, which can lead to bone pain and fractures. In addition, the disease often causes Mutant An individual who differs from the parental strain as a result of mutation.
A form of cancer that affects plasma cells which are special white blood cells that produce antibodies, the agents our bodies use to help fight infection. The disease can cause tumors to grow in bones leading to bone pain and fractures.
A cancer that affects blood plasma cells. The disease causes the growth of tumors in many bones, which can lead to bone pain and fractures. In addition, the disease often causes kidney problems and lowered resistance to infection.
The Condition"...Recurrent infection -- Increased numbers of myeloma cells can also decrease the production of infection-fighting white blood cells, leading to reduced immunity and the possibility of frequent recurrent infections, such as bacterial pneumonia, urinary-tract infections, and shingles..."
The Condition"...Fatigue -- As the number of malignant plasma cells increases in the bone marrow, the growth and development of red blood cells in the bone marrow may be suppressed, leading to low levels of red blood cells in the blood (anemia)..."
Multiple myeloma (also known as MM, myeloma, plasma cell myeloma, or as Kahler's disease after Otto Kahler) is a type of cancer of plasma cells which are immune system cells in bone marrow that produce antibodies. Its prognosis, despite therapy, is generally poor, and treatment may involve chemotherapy and stem cell transplant. It is part of the broad group of diseases called hematological malignancies.
The Condition"...cause a variety of symptoms, including loss of appetite, fatigue, muscle weakness, restlessness, difficulty in thinking or confusion, constipation, increased thirst, increased urine production, and nausea and vomiting..."