A variation of bone marrow transplantation in which immature blood cells, called stem cells, are taken from the patient's blood and stimulated with growth factors to produce more stem cells. These are later returned to the patient by transfusion.

a complex procedure to replace unhealthy stem cells with healthy ones

a form of treatment for leukemia and lymphoma

a procedure that is performed to repair the damage caused by high-dose chemotherapy

a procedure that is used in conjunction with high-dose chemotherapy, which is frequently more effective than conventional chemotherapy in destroying myeloma cells

a procedure that replaces the stem cells that are destroyed by high-dose chemotherapy and/or radiation therapy with healthy stem cells

a procedure that utilizes high doses of therapy to kill more cancer cells than conventional doses

see Peripheral Blood Stem Cell Transplant.

To treat cancer and other conditions chemotherapy and/or radiation may be given to patients. As a result the patient’s bone marrow may be injured or destroyed. In a stem cell transplant the patient is given an infusion of healthy stem cells. The stem cells migrate to the cavities of the large bones and begin producing blood cells. Stem cell transplants can be allogeneic or autologous depending on what kind of disease the patient has.

The replacement of a patient's own bone marrow stem cells after high-dose chemotherapy (HDC). Stem cells are the origins of all blood cells, from which all other cells are developed.

moving stem cells (immature cells that give rise to particular kinds of cells) from one person to another. Transplant also is done after the patient receives chemotherapy by taking stem cells from a person, cleansing them, storing them, and returning them to the same person.

Treatment for cancer. Stem cell transplant is similar to bone marrow transplant, but does not need an anaesthetic to collect the cells and recovery can be quicker. But donor transplants (allogeneic transplant) cannot be done with stem cells yet. So if a donor transplant is needed, a bone marrow transplant will still be done. Very high doses of chemotherapy are given to kill cancer cells. This also kills the bone marrow which contains all the developing blood cells. For a transplant, the very early blood cells normally found in the bone marrow are collected from the blood, frozen and stored. The stem cells can then be given back through a drip after the high dose chemotherapy is over. They find their way back inside the bones and start to make blood cells again.

The process of infusing healthy stem cells into persons who have undergone high-dose chemotherapy for one of many forms of leukemia, immunodeficiency, lymphoma, anemias or metabolic disorders.  Healthy stem cells are collected from bone marrow, peripheral blood and umbilical cord blood.  Once the healthy stem cells are infused into the patient's blood stream, the cells move from the blood vessels to the center of the bones where they begin making new blood cells. A stem cell from the blood of the umbilical cord and placenta.

Replacement of diseased bone marrow with healthy stem cells, for example in leukaemia. A special machine is used to remove stem cells from the blood of a donor. These are stored and given to the patient through a drip, after high dose chemotherapy has been used to kill off the patient's own bone marrow.

A type of cancer treatment. It is like a bone marrow transplant, except that you get the stem cells themselves.

A way of giving healthy bone marrow cells back to a patient after high dose chemotherapy treatment. A special machine is used to remove stem cells from the blood. These are stored and given back to the patient through a drip, after the chemotherapy.

Transplantation of stem cells from various sources has provided improvement in animal spinal neurodegenerative disease models such as stroke, epilepsy, Parkinson's and spinal cord injury. Human trials are promising, but not complete.

See bone marrow transplant.

The process of infusing healthy stem cells into persons who have undergone high-dose chemotherapy for one of many forms of leukemia, immunodeficiency, lymphoma, anemias, or metabolic disorders. There are three types of stem cell transplants: autologous, allogeneic and syngeneic. Healthy stem cells are collected from bone marrow, peripheral blood, and umbilical cord blood. Once the healthy stem cells are infused into the patient's blood stream, the cells move from the blood vessels to the center of the bones, where they begin making new blood cells. (See Autologous, Allogeneic, and Syngeneic.)

also known as non-myeloablative or ÒminiÓ transplants. Lower doses of chemotherapy and possibly radiation are used as the conditioning regimen, followed by the infusion of donor stem cells. In this type of transplant, the purpose is not to replace the patients destroyed marrow cells, as the patientÔs marrow function would return to normal if donor cells were not administered. The conditioning regimen is given to suppress the patient' s marrow function for a short time period allowing the donor cells to engraft . The donor cells are given in order to create a graft-versus-malignancy effect. The term ÒminiÓ transplant, however, is somewhat misleading. Although patients receive less toxic dosages of chemotherapy and radiation, and may feel well early in the post transplant process, they are still at risk to develop serious and potentially life-threatening side effects. These side effects often begin 30-60 days post-transplant when the new immune system is gaining strength.

procedure used to restock the bone marrow when it has been destroyed by chemotherapy, radiation, or disease. Stem cells can be taken from bone marrow or circulating blood and later, in the lab, stimulated with growth factors to produce more stem cells which are transfused into the patient. Stem cells may be the patient?s own (autologous), or may come from someone else (allogeneic). Bone marrow transplants (BMTs) were the first method for replacing stem cells.