Process by which certain types of cells are removed from stem cells prior to infusion into the patient. In autologous transplantation, stem cells may be purged to remove lingering cancer cells. In allogeneic transplants, donor stem cells may be purged to remove T-lymphocytes that cause graft-versus-host disease
Removal cancer cells from stem cells extracted from a cancer patient prior to re-implanting them
The process by which tumor cells are removed from the marrow or blood stem cell suspension that are to be used for an autologous transplant. The stem cells used in an autologous transplant are obtained from a patient with leukemia, lymphoma, or myeloma. The patient is usually treated to induce a remission before the stem cells are harvested but some inapparent tumor cells are probably always present. Purging is used to try to minimize the chance of returning tumor cells to the patient with the stem cells infusion after intensive and hopefully curative cytotoxic treatment is given.
A process to remove certain components found in bone marrow or stem cell harvests. In an autologous harvest, purging may be used to remove any remaining cancerous cells. In an allogeneic harvest, purging may be used to remove components of the donor collection that can cause graft-versus-host disease.
The process of removing certain types of cells from the stem cell product before transplanting it to a patient. In autologous transplants, marrow may be purged of lingering cancer cells.
in cancer treatment purging refers to the removal of cancer or T cells in bone marrow or stem cells prior to BMT or PBSCT. adiation Therapy: Treatment with high-energy radiation from X-rays or other sources of radiation (like radioisotopes).
Removing stagnant air or water from sampling zone or equipment prior to sample collection.
Removal of tumour cells from harvested bone marrow or blood before autologous transplantation.
Consists of exposing the cancer-contaminated bone marrow to a variety of cancer-killing agents prior to cryostorage.