A marked decrease in the number of granulocytes. Granulocytes are a type of white blood cell filled with microscopic granules that are little sacs containing enzymes that digest microorganisms. See the entire definition of Agranulocytosis
A significant decrease in the number of granulocytes, a type of blood cells that contain microscopic granules containing enzymes that destroy microorganisms. They are part of the innate immune system but do not respond to specific antigens as do the B- and T-cells.
disorder in which there is a severe acute deficiency of certain blood cells as a result of damage to the bone marrow by toxic drugs or chemicals. It is characterised by fever, with ulceration of the mouth and throat, and throat, and may lead rapidly to prostration and death. Treatment is by the administration of antibiotics in large quantities. when feasible, transfusion of white blood cells may be life-saving.
An acute condition characterised by an abnormally low level of white blood cells, which impairs the bodyâ€(tm)s ability to fight infection and which therefore has the potential to be fatal. It can be a side effect of the atypical antipsychotic, clozapine.
Agranulocytosis (literally meaning an increase of agranulocytes or more commonly, a lack of granulocytes) is an acute condition involving a severe and dangerous leukopenia (reduction in the number of white blood cells) in the body. Concentrations of granulocytes (a class which includes neutrophils, basophils and eosinophils) can often drop to below 500 cells/mmÂ³ of blood), less than a sixth of the reference value of 3-10 x 103 cells/mmÂ³.