any condition in which the number of leukocytes or white cells in the circulating blood is abnormally high; a white cell count of 10,000 or more per cubic millimeter. This is a non-specific finding. Generally when there is an increase in red cell production, the white cell count is elevated. If there are many immature red blood cells present in the circulation, the white cell count as done by a machine is elevated. A 'corrected white count' is then done manually with a microscope.[close window
Leukocytosis is an increased number of WBCs. It is usually caused by an increase in the number of circulating neutrophils (neutrophilia), though lymphocytosis (especially with leukemia) occasionally produces leukocytosis. Absolute values of individual WBC types provide much more diagnostic specificity than a simple WBC count. Exercise, fear and digestion cause physiologic leukocytosis. Infection, rapidly growing neoplasms, acute hemolysis, hemorrhage, intoxication, leukemia and trauma cause pathologic leukocytosis.
An abnormally high number of leukocytes in circulation. This condition can occur during acute infection, inflammation, hemorrhage, and other conditions. Generally, a cell count greater than 10,000 cells/mm³ indicates leukocytosis.
Leukocytosis is an elevation of the white blood cell count (the leukocyte count) above the normal range. The normal adult human leukocyte count in peripheral blood is 4.4-10.8 x 103/L. A white blood count of 11.0 or more suggests leukocytosis.