Definitions for "myelofibrosis"
Fibrosis of the bone marrow.
reactive bone marrow fibrosis usually accompanying neoplastic cell proliferation.
A progressive disease in which the cells of the bone marrow that produce scarring rather than blood cells begin to multiply rapidly. This leads to anemia and enlargement of the spleen and liver. Myelofibrosis can occur as part of a myeloproliferative disorder, or as a result of another unrelated condition.