Definitions for "Nucleoside Reverse Transcriptase Inhibitor"
an antiviral drug used against HIV; is incorporated into the DNA of the virus and stops the building process; results in incomplete DNA that cannot create a new virus; often used in combination with other drugs
this is a type of drug used against HIV infection that also inhibits the production of HIV's genetic material (for example, zidovudine, didanosine, zalcitabine, stavudine)
a nucleoside analog antiretroviral drug whose chemical structure is made up of a modified version of a natural nucleoside. These compounds suppress reproduction of retroviruses by interfering with the reverse transcriptase enzyme. The nucleoside analogs cause premature termination of the proviral (viral precursor) DNA chain. All NRTIs require phosphorylation, (the process of introducing a phosphate group into an organic molecule), in the host's cells prior to their incorporation into the viral DNA.