A compound, naturally occurring in plants, that breaks down the enzyme protease, which inhibits the replication and development of certain cells such as cancers and viruses, including HIV
Antiviral drugs that act by inhibiting the virus protease enzyme, thereby preventing viral replication. Specifically, these drugs block the protease enzyme from breaking apart long strands of viral proteins to make the smaller, active HIV proteins. If the larger HIV proteins are not broken apart, they cannot assemble themselves into new functional HIV particles. FDA has approved the following protease inhibitors as drugs to treat HIV disease: Saquinavir (Invirase, Fortovase), Indinavir (Crixivan), Nelfinavir (Viracept), Ritonavir (Norvir), and Amprenavir (Agenerase).
A kind of HIV med that stops HIV from making copies of itself by blocking the last step in the process. HIV's protease enzyme breaks apart long strands of viral protein into the smaller, separate proteins that make up the core of new virus. Protease inhibitors keep the enzyme from cutting up the long viral chain - and if the larger HIV proteins are not broken apart they can't make themselves into new HIV particles that can leave the CD4 cell and infect other cells.
an antiviral drug used against HIV; interrupts HIV replication by binding and blocking HIV protease; often used in combination with other drugs
a type of drug that cripples the enzyme protease
a type of anti-HIV drug that works by preventing the production of an enzyme, protease, that HIV needs to replicate.
A substance that restricts the action of protease. Protease is an enzyme that digests protein.
a drug that works against HIV (or other infections) by inhibiting the formation of proteins (for example, saquinavir, indinavir, amprenavir, lopinavir, ritonavir, nelfinavir, atazanavir)
one of a class of anti-HIV drugs designed to inhibit the enzyme protease and interfere with virus replication. Protease inhibitors prevent HIV precursor proteins from dividing into smaller cells of active proteins, a process that normally occurs when HIV reproduces.
a class of anti-HIV drug that prevents creation of an HIV-specific protease.
a drug (e.g., saquinavir, indinavir, ritonavir, nelfinavir, amprenavir) that blocks the action of the HIV protease enzyme, which cuts newly made viral proteins, thereby preventing viral replication.
one of a class of anti-HIV drugs designed to inhibit the enzyme protease and interfere with virus replication. Protease inhibitors prevent the cleavage of HIV precursor proteins into active proteins, a process that normally occurs when HIV replicates.
a drug (e.g., saquinavir, ritonavir, indinavir, nelfinavir, amprenavir) that blocks the action of the HIV protease enzyme, thereby preventing viral replication. Unlike reverse transcriptase inhibitors, protease inhibitors can inhibit HIV replication in cells that are already infected.
A type of antiretroviral drug designed to stop the protease enzyme from working. [example: Crixivan(tm) (indinavir) IDV
Drugs that block the action of proteasomes, cellular complexes that break down proteins.
any class of drugs that interfere with replication of the AIDS virus (HIV) by blocking an enzyme (protease) necessary in the late stages of its reproduction. (Indinavir)
a kind of HIV medicine that keeps the virus from making new copies of itself.
A drug that binds to and blocks HIV protease from working, thus preventing the production of new infectious viral particles.
A drug that works by inhibiting HIV protease, an aspartyl enzyme essential for the replication of the virus. Protease inhibitors include amprenavir, indinavir, nelfinavir, ritonavir and saquinavir and are used in combination therapies to treat HIV/AIDS.
A class of antiretroviral drug that interferes with the replication of HIV by inhibiting the HIV enzyme called "protease."
In biology and biochemistry, protease inhibitors are molecules that inhibit the function of peptidases (old name: protease, hence the term protease inhibitor). Many naturally-occurring protease inhibitors are proteins.