Definitions for "Nucleoside Analog"
also known as NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR, NRTI): a compound (e.g., AZT, d4T, 3TC) that mimics one of the building blocks of DNA. These compounds suppress retroviral replication by interfering with the reverse transcriptase enzyme.
An HIV drug, acting to replace natural nucleosides and block the completion of the viral DNA chain during infection of a new cell by HIV.
(See Purine analog).