The set of nucleotide pairs coding for one particular amino acid in the sequence of several thousand nucleotides in a gene; addition or deletion of one or two nucleotide pairs shifts the reading frame from that point to the end of the molecule.
The particular nucleotide sequence that starts at a specific point and is then partitioned into codons. The reading frame may be shifted by removing or adding a nucleotide(s). This would cause a new sequence of codons to be read. For example, the sequence CATGGT is normally read as the two codons: CAT and GGT. If another adenosine nucleotide (A) were inserted between the initial C and A, producing the sequence CAATGGT, then the reading frame would have been shifted in such a way that the two new (different) codons would be CAA and TGG, which would code for something completely different. See DNA, Codon, Mutation, Nucleotide.
In a protein-coding mRNA, the translation machinery has to start at a particular point in order to read off the correct sets of three nucleotides (codons) as it moves along the RNA. There are three possible reading frames in any sequence, only one of which usually encodes a functional protein.
The phase in which nucleotides are read in sets of three to encode a protein; an mRNA molecule can be read in any one of three reading frames.
The succession of codons determined by reading nucleotides in groups of three from a specific initiation codon.
Linear sequence of codons in a protein-coding gene starting with the initiation codon and ending in the termination codon.
In protein-coding mRNA three nucleotides code for one amino acid, therefore there are three different ways to interpret a given message, or three reading frames, depending on the starting point. In DNA, there are additionally three potential reading frames on the reverse strand.
A codon sequence that is comprised from reading DNA bases in groups of three from a specific start site, usually the beginning of a gene. Insertion or deletion mutations to a gene's DNA sequence thus disrupt the normal reading frame.
The DNA nucleotide corresponding to the first codon position in mRNA. 332
The sequence of nucleotides which is read as consecutive triplets during translation of mRNA into protein. A sequence of codons that continues without encountering a stop codon is called an open reading frame (ORF). For a sequence of double-stranded DNA there are six possible reading frames; three in the forward direction, and three in the reverse direction. A sequence of DNA will often have one ORF, but in some cases a sequence of DNA will include overlapping ORFs that encode distinct polypeptides.
The way in which the genetic code in mRNA is read as triplets by the ribosome.
The register in which a nucleic acid sequence is read, in 3-base increments.
A series of triplets beginning from a specific nucleotide. Each triplet is represented by a single amino acid in the protein synthesized. The reading frame defines which sets of three nucleotides are read as triplets in the DNA, and hence as codons in the corresponding mRNA; this is determined by the initiation codon, AUG. Thus the sequence AUGGCAAAAUUUCCC would read as AUG/GCA/AAA/UUU/CCC/ and not as A/UGC/CAA/AAU/UUC/CC. Depending on where one begins, each DNA strand contains three different reading frames. See open reading frame, overlapping reading frames.
(synonym: exon) A sequence of messenger RNA that is translated into an amino acid chain, three bases at a time, each triplet sequence coding for a single amino acid
A sequence of codons beginning with an initiation codon and ending with a termination codon; also the way in which nucleotides are read in groups of three (codons) to specify the polypeptide coded by a gene.
The way an mRNA is read as a series of triplet codons during translation. There are three possible reading frames for any mRNA, and the correct reading frame is set by recognition of the AUG initiation codon.
The codon sequence that is determined by reading nucleotides in groups of three from some specific start codon.
The stretch of triplet sequence of DNA that encodes a protein. The reading frame is designated by the initiation or start codon and is terminated by a stop codon. As an example, the sequence CAGAUGAGGUCAGGCAUA potentially can be translated as follows: Position 1 CAG AUG AGG UCA GGC AUA gln met arg ser gly ile Position 2 AGA UGA GGU CAG GCA UA arg trp gly gln ala Position 3 CA GAU GAG GUC AGG CAU asp glu val arg his Figure 8 Open Reading Frames DNA (through RNA) uses a triplet code to specify the amino acid for a given protein. As can be seen above, a given strand of DNA has three possible starting points (position [or reading frame] one, two, or three). Since both strands of DNA can be translated into RNA and then into protein, a sequence of double helical DNA can specify six different reading frames.
One of the three possible ways of reading a nucleotide sequence. As the genetic code is read in non-overlapping triplets (codons) there are three possible ways of translating a sequence of nucleotides into a protein, each with a different starting point. For example, given the nucleotide sequence: AGCAGCAGC, the three reading frames are: AGC AGC AGC, GCA GCA, CAG CAG.
The sequence of nucleotide triplets (codons) that runs from a specific translation start codon in a mRNA to a stop codon. Some mRNAs can be translated into different polypeptides by reading in two different reading frames. ( Figure 4-21)
In biology, a reading frame is a contiguous and non-overlapping set of three-nucleotide codons in DNA or RNA. There are 3 possible reading frames in a m RNA strand and six in a double stranded DNA molecule. This leads to the possibility of overlapping genes and there may be many of these in bacteria.
