Alkaline phosphatase is an enzyme that catalyses the hydrolysis of phosphoric acid esters under conditions of alkaline pH. In humans, the level of alkaline phosphatase in the blood is measured as part of the assessment of liver function. In the blood, the enzyme also breaks down phosphates required for mineralization of bone. There are two distinct forms of the enzyme, liver alkaline phosphatase and bone alkaline phosphatase.
A liver enzyme, measured through a blood test, that indicates the health of the liver. Lower counts are better. Levels may go up because of hepatitis and other infections, or because of drug toxicities
An enzyme that indicates inflammation or diseases of the biliary tract. The enzyme also comes from the intestine, bones, and placenta. These separate sources can be identified by electrophoresis. This separates out the different types of enzyme.
A group of enzymes that belong to the class known as hydrolases. They are thought to play an important role in the transport of sugars and phosphates in the intestine, bone, kidney and placenta. Elevated serum levels of alkaline phosphatase activity may indicate liver disease.
An enzyme made in the liver , bone, and the placenta and normally present in high concentrations in growing bone and in bile. Alkaline phosphatase is released into the blood during injury and during such normal activities as bone growth and pregnancy . It is measured in a routine blood test. See the entire definition of Alkaline phosphatase
An enzyme in the blood commonly used in medical diagnosis. It is elevated in cases of bile obstruction (liver disease or cancer involving the liver) and in various bone diseases, including cancer involving the bone.
an enzyme. Doctors sometimes look for alkaline phosphatase to determine the condition of a patient's liver. Low counts are best. A high count suggests hepatitis or a drug toxicitity. (also abbreviated as alk phos)
A naturally occurring enzyme in the body released in larger amounts when bone is being formed. High levels indicate bone tissue formed at an abnormally high rate. Blood tests that detect high levels of alkaline phosphatase are one of the standard methods used to diagnose bone metastases.
An enzyme normally present in certain cells within the liver, bone, kidney, intestine and placenta. When the cells are destroyed in those tissues, more of the enzyme leaks into the blood, and levels rise in proportion to the severity of the condition.
Alkaline phosphatase (ALP) is a hydrolase enzyme responsible for removing phosphate groups in the 5- and 3- positions from many types of molecules, including nucleotides, proteins, and alkaloids. The process of removing the phosphate group is called dephosphorylation. As the name suggests, alkaline phosphatases are most effective in an alkaline environment.