To lay waste; to ruin; to ravage; as, a fire desolates a city.
leave someone who needs or counts on you; leave in the lurch; "The mother deserted her children"
reduce in population; "The epidemic depopulated the countryside"
devastate or ravage; "The enemy lay waste to the countryside after the invasion"
made uninhabitable; "upon this blasted heath"- Shakespeare; "a wasted landscape"
(1) deserted or uninhabited, as in: They washed up on the shore of a desolate island. (2) miserable, as in: I am desolate that you believed I could do a thing like that.