An inherited increase in the risk of developing a disease.
an inherited condition which is carried on the genetic material DNA. It makes an individual more likely to develop an illness.
Increased probability (compared to the general population) of developing a disease, due to the presence of one or more gene mutations. Genetic predispositions, unlike most 'single gene' genetic conditions, are modified by non-genetic influences, such as diet or smoking.
An inherited predisposition to a disease or disorder which is not due to a single gene cause and is usually the result of a complex interaction of the effects of multiple different genes, i.e. polygenic inheritance.
predetermined group of immune- response genes represented by HLA DR. Particular toxin illnesses are highly linked to presence of particular genotypes. While the genes donÂ't make patients ill, exposure to toxins will result in illness essentially only in those with the “susceptible” genotype. The HLA link to lack of antibody formation is a bridge from the innate immune response to the acquired immune response
Having a gene (or genes) that is(are) associated with an additional risk of falling ill to some common disease or to an inherited disorder; oftentimes refers to an increased risk of a specific illness after contact with a particular environmental agent.
Likelihood of acquiring a hereditary disease.
The state of being more likely than the average person to develop a disease as a result of genetics.
an inherited predisposition to a disease, especially cancer. Used particularly to describe predispositions that are higher than the background risk in the population. Can apply to the likelihood of higher risk in the presence of specific exposures. See Metabolic enzymes.
