The sequential breakdown of fatty substances in cells by chemical oxidation, leading eventually to the destruction of membranes within and surrounding the cell.

Refers to the oxidative degradation of lipids. This process proceeds by a free radical chain reaction mechanism. [See: Fluoride & the Brain | Fluoride & the Kidneys

Lipids are the most readily oxidizable class of biomolecules, so oxidative stress is most often monitored by measuring the products of lipid peroxidation. Lipid peroxidation is the result of an oxidative free radical attack on unsaturated fatty acids found in all cell membranes resulting in cell damage.