A family of antioxidant enzymes containing selenium which are important in the reduction of different hydroperoxides, including hydrogen peroxide which is involved in the irritation of the gastrointestinal tract and increase in perspiration. GLYCINE: Natural antacid and sweetener. Involved in the syntheses of DNA, phospholipids and collagen. May act as an inhibitory neurotransmitter.
An enzyme that is dependent upon selenium at the active site of use in the body for oxidation processes; may be linked to jaundice.
a 85,000 D tetrameric enzyme with four atoms of selenium incorporated as selenocysteine; protects the cell from oxidant damage.
An enzyme found in the cytoplasm and mitochondria, which acts in concert with GSH to reduce H2O2 to H2O. During this process, GSH is oxidized to produce GSSG.
an enzyme in the body that is a powerful scavenger of free radicals
An enzyme found in plants that speeds up oxidation reactions involving hydrogen peroxide or other peroxides. A chemical compound (peptide) found in plant and animal tissue that consists of glutamic acid, cysteine, and glycine. It is important in biological oxidation-reduction reactions and the activation of some enzymes.
An enzyme known for its antioxidant effects against peroxides. Its central element is selenium.
selenium - and - cysteine - containing enzyme which, with the required help of reduced glutathione, catalyzes the breakdown of peroxides, while controlling the potentially dangerous free radicals. It also directly scavenges free radicals.
an antioxidant enzyme that reduces hydrogen peroxide levels in fatty layers of cells.
Glutathione peroxidase (, ) is the general name of an enzyme family with peroxidase activity whose main biological role is to protect the organism from oxidative damage. The biochemical function of glutathione peroxidase is to reduce lipid hydroperoxides to their corresponding alcohols and to reduce free hydrogen peroxide to water. There are several isozymes encoded by different genes, which vary in celullar location and substrate specificity.
