This non-surgical procedure involves the administration of a medication(s) to induce an abortion. Medications (e.g., methotrexate, mifepristone, misoprostol) are used most frequently early in the first trimester of pregnancy. However, some medications (e.g., prostaglandin suppositories, injectable prostaglandins) may also be administered during the second trimester of pregnancy to induce abortion. Medications may be administered orally, by injection, or intravaginally.