A group of alkylating agents derived from mustard gas, with the sulfur replaced by nitrogen. They were formerly used as toxicants and vesicants, but now function as antineoplastic agent. These compounds are also powerful mutagens, teratogens, immunosuppressants, and carcinogens.

DNA alkylating agent, former war gas used during WW I and first cytotoxic drug successfully used to treat cancer; it has limited use today.

a toxic compound resembling mustard gas in structure; important in cancer treatment